Consequences from most medical interference
trials have disastrous to explain a beneficial consequence of vitamin C
supplementation on the chief or secondary preclusion of cardiovascular disease.
In the Women's Antioxidant Cardiovascular Study, a less vital expectancy trial
involving 8,171 women elderly 40 years or older with a the past of
cardiovascular disease, supplementation with 500 mg/day vitamin C for a mean of
9.4 years showed no overall effect on cardiovascular actions .likewise, vitamin
C supplementation (500 mg/day) for a denote follow-up of 8 years had no effect
on main cardiovascular events in male physicians enrolled in the Physicians'
Health Study II .Other clinical trials have generally examined the effects on
cardiovascular disease of supplements combining vitamin C with other
antioxidants, such as vitamin E and beta-carotene, making it more difficult to
isolate the possible contribution of vitamin C. The SU.VI.MAX study examined
the belongings of a combination of vitamin C (120 mg/day), vitamin E (30
mg/day), beta-carotene (6 mg/day), selenium (100 mcg/day), and zinc (20 mg/day)
in 13,017 French adults from the general inhabitants .After a center take notes
time of 7.5 years, the combined supplements had no result on ischemic
cardiovascular disease in either men or women. In the Women's Angiographic
Vitamin and Estrogen (WAVE) study, involving 423 postmenopausal women with at
least one coronary stenos is of 15%–75%, supplements of 500 mg vitamin C plus
400 IU vitamin E twice per day not only provided no cardiovascular benefit, but
significantly increased all-cause mortality compare with placebo .
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